It seems 2025 was the year of "the seemingly regular guy beating the shit out of everyone... and everyone beating the shit out of an unstoppable regular guy". There were at least three movies that all fit this trope: Love Hurts, Nobody 2, and Novocaine.
Novocaine places itself firmly in the middle of this regular guy action genre. All three have a ton of action and great fight sequences but only Nobody 2 had a thing that most resembled an actual plot... and eve n that had to be helped along by the nostalgia of a Midwesterner looking back at the Wisconsin dells from the 1970s. While Love Hurts didn't even pretend to have a plot and only used the "story" to set up fights, at least Novocaine was based on an amusing premise. Our hero Nate has a very rare diseases that means he cannot feel pain. In fact, he can't feel anything physical. It is like his entire body is effected by Novocaine. They make sure we know this by repeatedly showing us that he can't even chew solid food because he would never know if he were chewing his tongue. How he is able to keep his balance or grasp and hold things is beyond me... but that is putting way too much thought into this.
Guy can't feel pain. Guy can take unlimited abuse. Guy is like a superhero... a really shitty superhero but a superhero nonetheless. That is as much thinking you should do as you watch this. Because of the lack of feeling pain, some really bad shit happens to Nick and he just keeps getting up for more. That is the gimmick of the movie. Some of the action sequences are actually pretty cool or funny because of this premise.

And there are plenty of action sequences. I'd guess that at least 60% of the movie is action. When there isn't action, they make jokes about the action. It works as an hour and forty-five minute diversion but it probably isn't going to leave a lasting impression on the audience.
So what's good? Obviously the action. This is especially true of the new things a hero can do when he doesn't have any pesky pain to worry about. Just imagine what a person can do with broken glass in a fight if they don't have to worry about the pain it might cause them. I also love the show The Boys. Why does this matter? Well Nick is played by Jack Quaid who plays Huey on The Boys. Nick and Huey are basically the exact same character with different powers. If you like one, you'll like both. And I do. In addition, many of the jokes work very well. There are some interesting side characters along the way. But that's pretty much it. Some jokes and action. That's good enough for me.
What's bad? Well the entire movie is absurd. I get he can't feel pain but how does that make him a trained fighter? How is he able to stand toe to toe with actual badasses? And apparently concussions don't exist in this universe (or maybe they are like NFLer and certified "genius" Puka Nacua thinks and they are "only in your head"... get it... what an idiot). I get Nick can't feel pain but as far as I know, boxers don't get knocked unconscious by pain, they get knocked out by head trauma and Nick suffers lots of that. Finally, I have no idea why Nick is better at finding someone than the police. The entire movie is base don the idea that Nick simply must find the McGuffin... I mean girl. There is also way too much grpahic violence. I mean close up body torture type stuff. that is no my cup of tea.
All of this absurdity is why I put it after Nobody 2. But if you like a different twist on action, Novocaine is entertaining. Not awesome, but at least it's not boring.