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In molecular biology, a hybridization probe (HP) is a fragment of DNA or RNA, usually 15–10000 nucleotides long, which can be radioactively or fluorescently labeled. HPs can be used to detect the presence of nucleotide sequences in analyzed RNA or DNA that are complementary to the sequence in the probe. The labeled probe is first denatured into single stranded DNA (ssDNA) and then hybridized to the target ssDNA or…
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It doesn't happen quite as much as it used to, but when I was a kid, I can't tell you the number of TV shows that started out and then were abruptly cancelled after only a couple seasons or in the worst case a couple of episodes. This is going to be a loose series covering some of my favorites from over the years. Keep checking back because in my 40+ years on this earth I have amassed quite the list and you never kn…More
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