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• 
  @mikewick77(49)· 593d

  Citrate-Ascorbate Synthesis

  Ascorbate (C6H8O6) Citrate (C6H8O7)

  Ascorbate Ascorbic Acid

  Dihydroxyethyl Dihydroxyfuran

  Furan
  Lactone Ketogluconic Acid
  Enediol Carbonyl

  Ascorbic acid is a furan-based lactone of 2-ketogluconic acid. It contains an adjacent enediol adjacent to the carbonyl.

  Ascorbate Peroxidase Ascorbate Ferrireductase Ascorbate Dioxygenase Ascorbate Oxidase Glutathione-Ascorbate Cycle

  Transmembrane

  ..

  https://en.m.wikipedia.org/wiki/Chemistry_of_ascorbic_acid

  https://en.m.wikipedia.org/wiki/Mineral_ascorbates

  https://en.m.wikipedia.org/wiki/Ascorbate_peroxidase

  https://en.m.wikipedia.org/wiki/Ascorbate_ferrireductase_(transmembrane)

  https://en.m.wikipedia.org/wiki/Ascorbate_2,3-dioxygenase

  https://en.m.wikipedia.org/wiki/L-ascorbate_oxidase

  https://en.m.wikipedia.org/wiki/Glutathione-ascorbate_cycle

  ..

  Potassium Citrate Magnesium Sulfate

  Recent Updates on Anti-Inflammatory and Antimicrobial Effects of Furan Natural Derivatives

  https://pmc.ncbi.nlm.nih.gov/articles/PMC7443407/

  ..

  Vagus Nerve DMSO

  Collagen Elastin Proteoglycans Glucosamine Chondroitin

  https://www.americancancercenternigeria.com/shop/item.aspx?itemid=2

  The vagus nerve and the inflammatory reflex—linking immunity and metabolism

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4082307/

  ..

  Calcium (Ca2+) Hypercalcemia Intracellular Signaling Molecules Calcification Mitochondria Cellular Senescence

  Regulation and role of calcium in cellular senescence

  https://www.sciencedirect.com/science/article/abs/pii/S0143416023000131

  Mitochondrial Dysfunction: Cause or Consequence of Vascular Calcification

  https://pmc.ncbi.nlm.nih.gov/articles/PMC8010668/

  Microglial Potassium Channels: From Homeostasis to Neurodegeneration

  https://pmc.ncbi.nlm.nih.gov/articles/PMC8698630/

  Neuroinflammation: The Devil is in the Details

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5025335/

  ..

  Lipedema Edema Glycogen Phosphocreatine Bioenergetic Systems

  https://www.lipedema.org/research-grants/

  https://morethanfat.com/lipedema-and-nutrition/lipedema-nutrition-and-common-supplements

  Renal Dysfunction in Cirrhosis: Diagnosis, Treatment, and Prevention

  https://pmc.ncbi.nlm.nih.gov/articles/PMC1480573/

  ..

  Cold Shock Proteins Y-Box Binding Protein YB-1 DNA Binding Protein B DbpB M4 ipRGCs Potassium DMSO Methylene Blue Blue Light Optogenetics Melanopsin Leptin Cytokine Endocrine System Vagus Nerve

  Cold shock proteins: from cellular mechanisms to pathophysiology and disease

  https://biosignaling.biomedcentral.com/articles/10.1186/s12964-018-0274-6

  ..

  Potassium Hyperpolarization GABA-B Receptor G Protein Guanine Nucleotide Binding Protein Coupled Receptor GTPase Intracellular

  Potassium channel-based optogenetic silencing

  https://pmc.ncbi.nlm.nih.gov/articles/PMC6218482/

  Optogenetics. Engineering of a light-gated potassium channel

  blue-light-induced K(+) channel 1 (BLINK1) engineered by fusing the plant LOV2-Jα photosensory module to the small viral K(+) channel Kcv. BLINK1 exhibits biophysical features of Kcv, including K(+) selectivity and high single-channel conductance but reversibly photoactivates in blue light. Opening of BLINK1 channels hyperpolarizes the cell to the K(+) equilibrium potential.

  https://en.m.wikipedia.org/wiki/Hyperpolarization_(biology)

  https://en.m.wikipedia.org/wiki/GABAB_receptor

  https://en.m.wikipedia.org/wiki/G_protein-coupled_receptor

  ..

  Mitochondrial osmoregulation in evolution, cation transport and metabolism

  https://www.sciencedirect.com/science/article/pii/S0005272821000013

  As organisms evolved to have less sodium cations abundant cytosols and replace Na+ with K+ and over time with other osmolytic solutes, mitochondria were forced to keep pace in eukaryotes. Thus, mitochondria became more dependent on potassium cations as the major osmolyte.

  The nitrogen–potassium intersection: membranes, metabolism, and mechanism

  https://onlinelibrary.wiley.com/doi/10.1111/pce.12671

  Nitrogen is an essential constituent of a vast array of metabolites and structural compounds, including proteins, nucleic acids, chlorophyll, co-enzymes, phytohormones and secondary metabolites, while the main functions of K+ are as a major osmolyte and source of positive charge for electrical homeostasis and enzyme activation.

  ..

  WHAT ARE THE CONCENTRATIONS OF DIFFERENT IONS IN CELLS?

  https://book.bionumbers.org/what-are-the-concentrations-of-different-ions-in-cells/

  ..

  Toxic DNA Adduction Mallard Reaction Thiamine Nucleotide Asparagine Acrylamide Glycidamide Oxiranecarboxamide Amyloid Synuclein Lipofuscin

  Heparan Sulfate Glucosaminide Glycosaminoglycan

  Glycidamide inhibits the sodium/potassium ATPase protein present in the plasma membrane of nerve cells. Intracellular sodium increases and intracellular potassium decreases due to this inhibition. This causes depolarization of the nerve membrane. The depolarization triggers a reverse sodium/calcium exchange, which will cause calcium-mediated axon degeneration.

  ..

  N-acetylcysteine for chronic kidney disease: a systematic review and meta-analysis

  https://pmc.ncbi.nlm.nih.gov/articles/PMC8129408/

  The role of leptin in selected skin diseases

  https://pmc.ncbi.nlm.nih.gov/articles/PMC7532589/

  Molecule interacts with prion proteins to alter cell behaviour

  https://www.ualberta.ca/en/medicine/news/2014/april/prion-proteins-potassium-channels.html

  Lipofuscin-bound iron is a major intracellular source of oxidants: Role in senescent cells

  https://www.sciencedirect.com/science/article/abs/pii/S0891584910000638

  ..

  Intracellular Extracellular

  Lipofuscin Glycidamide

  vs

  Amyloidosis Prion

  Role of Intracellular Amyloid β as Pathway Modulator, Biomarker, and Therapy Target

  https://pmc.ncbi.nlm.nih.gov/articles/PMC9103247/

  Research in recent decades focused on the pathological role of extracellular amyloid β aggregation, widely neglecting the potential meaning of very early generation of amyloid β inside the cell.

  A central hallmark of the disease is the presence of amyloidogenic plaques, formed by deposition, accumulation, and aggregation of the amyloid β peptide (Aβ) in the brain. The second well-described pathophysiological characteristic are neurofibrillary tangles, which result from hyperphosphorylation of the microtubule-associated Tau protein, consequently leading to cytoskeletal changes in neurons.

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• 
  @mikewick77(49)· 635d

  LUCA Malaria Apicoplast Carboxysome Microcompartments Virus/Prion

  ..

  Pyrenoid functions revealed by proteomics in Chlamydomonas reinhardtii

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5826530/

  An example of intra-organellar compartmentalization is the pyrenoid in the chloroplasts of algae.

  ..

  Cellular origin of the viral capsid-like bacterial microcompartments

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5683377/

  Considering that BMC proteins have been detected in only ~17% of known bacteria and none in archaea, whereas PII proteins are among the most ancient, ubiquitous and versatile components of signaling systems in nature, it appears most likely that BMC-H proteins evolved from PII-like proteins. However, it cannot be ruled out that the two families of cellular proteins have diverged from a common ancestor in a more distant past.

  Major shell proteins that form bacterial microcompartments (BMC) are structurally similar to ubiquitous cellular proteins, such as PII and IF-1, and in some cases can be linked to those by sequence similarity as well. They propose that BMC-H and BMC-P proteins originated from cellular proteins with ancient folds - ferredoxin-like (PII) and OB.

  ..

  Integrated genomic and fossil evidence illuminates life’s early evolution and eukaryote origins

  https://pmc.ncbi.nlm.nih.gov/articles/PMC6152910/

  The oldest fossil remains that can be ascribed to crown-Eukaryota is ~1.1 Ga Bangiomorpha pubescens, which can be confidently assigned to the red algal total group (Rhodophyta).

  ..

  Two proteins residing in the apicoplast membranes that together constitute a functional apicoplast pyruvate carrier (APC) to mediate the import of cytosolic pyruvate. Depletion of APC results in reduced activities of metabolic pathways in the apicoplast and impaired integrity of this organelle, leading to parasite growth arrest.

  Mitochondrial Pyruvate Carrier

  https://en.m.wikipedia.org/wiki/Mitochondrial_pyruvate_carrier_1

  https://en.m.wikipedia.org/wiki/Mitochondrial_pyruvate_carrier_2

  https://en.m.wikipedia.org/wiki/Pyruvate_dehydrogenase_complex

  https://en.m.wikipedia.org/wiki/Pyruvate_dehydrogenase_deficiency

  https://en.m.wikipedia.org/wiki/Inborn_errors_of_carbohydrate_metabolism

  ..

  Red Algae Purple Earth Hypothesis

  Chloroplasts probably evolved following an endosymbiotic event between an ancestral, photosynthetic cyanobacterium and an early eukaryotic phagotroph. This event (termed primary endosymbiosis) is at the origin of the red and green algae (including the land plants or Embryophytes which emerged within them) and the glaucophytes, which together make up the oldest evolutionary lineages of photosynthetic eukaryotes, the Archaeplastida.

  The life history of red algae is typically an alternation of generations that may have three generations rather than two. Coralline algae, which secrete calcium carbonate and play a major role in building coral reefs.

  Red algae are divided into the Cyanidiophyceae, a class of unicellular and thermoacidophilic extremophiles found in sulphuric hot springs and other acidic environments, an adaptation partly made possible by horizontal gene transfers from prokaryotes, with about 1% of their genome having this origin, and two sister clades called SCRP.

  All extant eukaryotes descend from the last eukaryotic common ancestor (LECA), which is thought to have featured complex cellular organization. To gain insight into LECA biology and eukaryogenesis—the origin of the eukaryotic cell, which remains poorly understood—we reconstructed the LECA virus repertoire. We compiled an inventory of eukaryotic hosts of all major virus taxa and reconstructed the LECA virome by inferring the origins of these groups of viruses. The origin of the LECA virome can be traced back to a small set of bacterial—not archaeal—viruses. This provenance of the LECA virome is probably due to the bacterial origin of eukaryotic membranes, which is most compatible with two endosymbiosis events in a syntrophic model of eukaryogenesis. In the first endosymbiosis, a bacterial host engulfed an Asgard archaeon.

  ..

  Immortal Stem Cell Embryonic Stem Cell Telomere DNA Regeneration

  Cross-species metabolomic analysis identifies uridine as a potent regeneration promoting factor

  https://www.nature.com/articles/s41421-021-00361-3

  Uridine Pyrimidine Metabolism Yamanaka Factors

  EndoMac Progenitors

  ..

  Apicomplexa is the Protist (Invertebrate) host, Apicoplast is the Plastid (Plant Cell).

  all the complex classes & variation of species, is only the Protist, nothing mentioned regarding the Plastid, like its all the same thing, with different mitochondrial programming.

  what this means is all living creatures are from this LUCA Plastid, also known as Malaria, possibly Nanobe (space spore), possibly the immortal cell line, can be programed or reprogrammed to do anything.

  ..

  Many of these nucleus-encoded apicoplast-targeted (NEAT) proteins, especially non-transmembrane ones located in the lumen of the apicoplast, contain an N-terminal signal peptide.

  The general mechanism of FeS formation in the mitochondrion and apicoplast involves pyridoxal-phosphate-dependent cysteine desulfurases which liberate sulfur (S0) from cysteine and transfer it to relay proteins in the form of a persulfide. The sulfur is then transferred to a scaffold protein (or proteins), where the FeS is formed with iron. Subsequently, the clusters are transferred to apoproteins via carrier proteins. Mitochondrial proteins rely on the mitochondrial ISC (iron-sulfur cluster formation) pathway and proteins in the cytosol and nucleus rely on the CIA (cytosolic iron-sulfur protein assembly) pathway.

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• 
  @mikewick77(49)· 651d

  

  

  Magnesium Nitrogen Chlorophyll Polyphenol Green Yellow Copper

  ..

  Sulfylimines Methylphenylsulfoximine

  https://en.m.wikipedia.org/wiki/Sulfilimine

  Bond-Forming and -Breaking Reactions at Sulfur(IV): Sulfoxides, Sulfonium Salts, Sulfur Ylides, and Sulfinate Salts

  https://pubs.acs.org/doi/10.1021/acs.chemrev.9b00111

  https://pmc.ncbi.nlm.nih.gov/articles/PMC6661881/

  ..

  Prenylthiol Allicin

  Here’s the chemistry behind marijuana’s skunky scent

  https://www.sciencenews.org/article/marijuana-skunk-smell-cannabis-pot-plant-chemistry

  Oswald was surprised to find that prenylthiol and many of the other sulfurous suspects in cannabis share structural similarities with molecules found in garlic.

  ..

  CBD has already been proven effective medicine, and its fascinating how similar the Sulfoxide qualities of Cannabis Prenylthiol & Garlic Allicin.

  this could be the direction to replace big pharma.

  Hard-Tack the raw Cannabis into non-high food supliment.

  ..

  MSM Methylsulfonylmethane Sulfur Cycle

  Small Intestinal Absorption of Methylsulfonylmethane (MSM) and Accumulation of the Sulfur Moiety in Selected Tissues of Mice

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5793247/

  HOW HISTAMINE AND SULFUR ARE RELATED

  https://www.drlaurendeville.com/how-histamine-and-sulfur-are-related/

  Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5372953/

  Sulfation Pathways During Neurodevelopment

  https://pmc.ncbi.nlm.nih.gov/articles/PMC9047184/

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• 
  @mikewick77(49)· 676d

  Caramelization Modified Starch Polyphenol Synthesis

  https://en.m.wikipedia.org/wiki/Caramelization

  https://en.m.wikipedia.org/wiki/Modified_starch

  The rate of caramelization is generally lowest at near-neutral acidity (pH around 7), and accelerated under both acidic (especially pH below 3) and basic (especially pH above 9) conditions.

  ..

  Fisetin vs Lipofuscin HMF

  https://en.m.wikipedia.org/wiki/Fisetin

  https://en.m.wikipedia.org/wiki/Hydroxymethylfurfural

  https://en.m.wikipedia.org/wiki/Histamine_H1_receptor

  https://en.m.wikipedia.org/wiki/Sirtuin

  ..

  Impacts of selected dietary polyphenols on caramelization in model systems

  https://www.sciencedirect.com/science/article/abs/pii/S0308814613008303?via%3Dihub

  HMF causes anaphylactic symptoms by acting as a H1 receptor agonist

  https://www.sciencedirect.com/science/article/abs/pii/S0006295220302367

  5-HMF induces anaphylactoid reactions in vivo and in vitro

  https://pubmed.ncbi.nlm.nih.gov/33102144/

  Polyphenols: From Theory to Practice

  https://pmc.ncbi.nlm.nih.gov/articles/PMC8621732/

  ..

  Chalcone Chalconoid Anthocyanin

  Polyphenol Quercetin Fisetin Ellagitannin Gingerol Kaempferol Resveratrol Oleuropein Secoiridoid

  Indole Alkaloid Tryptophan Melatonin Serotonin

  https://pubchem.ncbi.nlm.nih.gov/compound/Fisetin

  C15H10O6

  https://pubchem.ncbi.nlm.nih.gov/#query=C15H10O6

  https://en.m.wikipedia.org/wiki/Chalcone

  https://en.m.wikipedia.org/wiki/Chalconoid

  ..

  Arginine Taurine

  Life Extension

  Biophotonics

  https://en.m.wikipedia.org/wiki/Biophotonics

  Interleukin 10

  https://en.m.wikipedia.org/wiki/Interleukin_10

  ..

  https://en.m.wikipedia.org/wiki/Amino_sugar

  https://en.m.wikipedia.org/wiki/Aminoglycoside

  https://en.m.wikipedia.org/wiki/Aminocyclitol

  ..

  https://www.healthyandnaturalworld.com/health-benefits-of-apple-cider-vinegar-and-honey/

  ..

  Sodium rutin ameliorates Alzheimer’s disease–like pathology by enhancing microglial amyloid-β clearance

  https://pmc.ncbi.nlm.nih.gov/articles/PMC6393001/

  Sodium Rutin

  https://en.m.wikipedia.org/wiki/Rutin

  Aryne Benzyne
  Tetrahedral Molecule

  The hexadehydro-Diels-Alder reaction: Benzyne generation via cycloisomerization of tethered triynes

  https://pmc.ncbi.nlm.nih.gov/articles/PMC8008985/

  https://en.m.wikipedia.org/wiki/Alkyne

  ..

  Rutin is Quercetin Polyphenol.

  been testing Polyphenol Synthesis by Caramelization of Honey with Vinegar (&/or Citric Acid).

  its very powerful stuff, tastes like genger bread cookies, add some Sea Salt & GlyNAC to that, for a really interesting reaction.

  the general goal was to make Amino Acids & Enzymes Activators, to feed mitochondria, but it may also be a medicine.

  tried Honey, Vinegar & Mineral combinations for a few years, slowly testing the outcome, ultimately it must be boiled, otherwise it causes Ph problems.

  no matter how much Base is added to the Acids, ultimately it never stabilizes, by cooking or caramelization the molecules bind & balance the Ph.

  magnetic & superconducting properties C60 of carbon-alkali.

  almost like Graphene, Benzene or Fulleride, but more like a supercharged, stabilized & reduced Polyphenol Tetrahedron molecule.

  i dont particularity trust C60 because of the manufacturing methods, reduced oxygen combustion of Carbon & Chloride.

  my idea is to mix everything together and cook it down into a charged Carbon putty.

  acting as both a food supplement & medicine.

  basically a supplement compound or molecule that is similar to Graphene & C60 electrically, but not for cybernetics, but for Telomere detoxifying & enhancing properties.

  if the universe is electric & holographic, galactic web of charged plasma data transfer, thats the computer i want into.

  Telomere & DNA electricity as an antenna for cosmic mind interface, if the enemy wants the worst kind of outcome, then i want the best possible outcome.

  the structure of Peptide requires binding minerals complex, everything has to zip & lock together correctly.

  Enzimes unzipping toxic acid sludge, Amino Acids zipping Telomeres, as a single unit compound.

  this is two opposite directions of the same general idea.

  making the medicine incorrectly would cause the opposite effect, instead of cleaning & repairing, would just make a bigger sticky binding mess.

  the bad version having none, just Carbon & Oxygen alone.

  this is mirroring everything to do with Osmolyte.

  ..

  Honey Vinegar Minerals: (equil amounts) Calcium Magnesium Sodium Potassium

  boiled together

  remove bottom soot

  add:

  Niacin Thiamine NAC

  ..

  most recent testing is finally giving me multiple good results without problems.

  Honey (Molasses) 1/2 Cup Vinegar (Citric) 1/2 Cup

  Minerals: 1 Spoon Each

  Calcium Magnesium Sodium Potassium

  Boil together, then add 1 Spoon each

  B1 Thiamine B3 Niacin NAC

  ..

  pretty dang powerful, the Sugar, Acid & Salt Base need to be boiled together, the Ph just wont stabilize no matter what ratio.

  i think it becomes a polyphenol like compound, but that alone is still not strong enough to finish the battle.

  the B vitamins are just so powerful, but seem to need the Polyphenol & salts to become a medicine like Fenbendazole.

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• 
  @mikewick77(49)· 710d

  Raccoon Juice

  HVM Honey Vinegar Minerals

  SAM Sugar Acid Minerals

  ..

  Magnesium Dependent Osmotic, Enzymatic Activation & Methylation Transition of Hydrogen, Carbon, Nitrogen & Sulfur for Mitochondrial Metabolism ATP.

  Glycine Thiazole Cysteine Choline Magnesium

  Glynac Thiamine Fenbendazole

  NAC MSM TMG ACH IHN

  Acetylcysteine Methylsulfonylmethane Trimethylglycine Acetylcholine Inositol Nicotinate

  ..

  https://dralexrinehart.com/articles/glycine-and-nac/

  ..

  https://en.m.wikipedia.org/wiki/Sugar_acid

  https://en.m.wikipedia.org/wiki/Pyridoxal

  https://en.m.wikipedia.org/wiki/Pyridoxal_phosphate

  https://en.m.wikipedia.org/wiki/Transamination

  ..

  Skin Minerals: Key Roles of Inorganic Elements in Skin Physiological Functions

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181837/

  However, one should consider the fact that many mineral elements also constitute integral building blocks of the living matter, being chemically bound to “organic” molecules such as amino acids, lipids, nucleotides, and carbohydrates.

  Organic osmolytes as compatible, metabolic and counteracting cytoprotectants in high osmolarity and other stresses

  https://journals.biologists.com/jeb/article/208/15/2819/15754/Organic-osmolytes-as-compatible-metabolic-and

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• 
  @mikewick77(49)· 739d

  

  Spindle Apparatus Mitotic Spindle Microtubule Fenbendazole Benzimidazole Mebendazole

  https://en.m.wikipedia.org/wiki/Spindle_apparatus

  ..

  Mebendazole works by selectively inhibiting the synthesis of microtubules via binding to the colchicine binding site of β-tubulin, thereby blocking polymerisation of tubulin dimers in intestinal cells of parasites.

  Mebendazole has an impact on mammalian cells, mostly by inhibiting polymeration of tubulin dimers, thereby disrupting essential microtubule structures such as mitotic spindle.

  Mebendazole sometimes causes diarrhea, abdominal pain, and elevated liver enzymes. In rare cases, it has been associated with a dangerously low white blood cell count, low platelet count, and hair loss,[12][13] with a risk of agranulocytosis in rare cases.

  ..

  Mitosis, Focus on Calcium

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247304/

  Fundamentals of Cellular Calcium Signaling: A Primer

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942118/

  The complex nature of calcium cation interactions with phospholipid bilayers

  https://www.nature.com/articles/srep38035

  Calcium Dysregulation and Homeostasis of Neural Calcium in the Molecular Mechanisms of Neurodegenerative Diseases Provide Multiple Targets for Neuroprotection

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122891/

  Mitochondrial Calcium Deregulation in the Mechanism of Beta-Amyloid and Tau Pathology

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564294/

  Combination of calcium and magnesium ions prevents substrate inhibition and promotes biomass and lipid production

  https://www.sciencedirect.com/science/article/abs/pii/S2211926416300637

  Synthesis and Chemical and Biological Evaluation of a Glycine Tripeptide Chelate of Magnesium

  https://pmc.ncbi.nlm.nih.gov/articles/PMC8122334/

  Renal Control of Calcium, Phosphate, and Magnesium Homeostasis

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491294/

  ..

  Albumin Amino Acid Proteins Hydrogen Calcium Ions Osmotic Balance Osmoregulation Glycine Betaine

  This inhibition could be relieved by addition of excess free calcium, completing the circle, and demonstrating a fundamental role for calcium in cell division.

  High intakes of sodium, protein and potassium has been linked to an increase in calcium excretion through the urine, feces and sweat. Large intake of caffeine increases calcium excretion and inhibits absorption of calcium.

  both hydrogen ions and calcium are bound to serum albumin, when blood becomes alkalotic, the bound hydrogen ions dissociate from albumin, freeing up the albumin to bind with more calcium and thereby decreasing the freely ionized portion of total serum calcium.

  ..

  The 2-to-1 Calcium-to-Magnesium Ratio

  https://www.nutritionalmagnesium.org/optimum-calcium-magnesium-ratio/

  Mystery solved: Why seashells’ mineral forms differently in seawater

  Century-old riddle about aragonite formation is unraveled by scientists’ atomistic simulation.

  https://news.mit.edu/2015/why-seashell-mineral-forms-differently-in-seawater-0302

  ..

  Preparation method of fenbendazole

  https://patents.google.com/patent/CN103242238A/en

  https://en.m.wikipedia.org/wiki/Colony-stimulating_factor

  ..

  Glycan Polyporaceae Polysaccharide

  Turkey Tail Mushroom Coriolus Versicolor

  PSP Polysaccharide Peptide

  PSK Polysaccharide Krestin

  Immunomodulatory Properties of Coriolus versicolor: The Role of Polysaccharopeptide

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592279/

  Trametes versicolor (Coriolus versicolor) Polysaccharides in Cancer Therapy: Targets and Efficacy

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277906/

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• 
  @mikewick77(49)· 747d

  

  Amyloplast Leucoplast Amoeboid

  Plastome Proteinoplast Cryptosporidium Carotenoid

  Amyloplasts are specifically a type of leucoplast, a subcategory for colorless, non-pigment-containing plastids.

  https://en.m.wikipedia.org/wiki/Leucoplast

  ..

  Dengue Fever Mechanism of infection:

  this looks like a Endosymbiont DNA parasite, look at how many words they use to scribble a narrative.

  they map out the virus pathways & ignore the parasite symbiont.

  its impossible for me to explain, because i cant prove it, but it just looks like a filibuster of big words.

  if viruses are not alive, why do they always seem to get more dangerous, evolve.

  instead of integrating into the biological system immunity, it hides instead.

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• 
  @mikewick77(49)· 756d

  

  

  Glycine Betaine Choline Inositol Osmolyte Lipotropic Plaque Cholesterol Phosphorus Calcium

  CH3 Methyl Methane Alkane Hydrogen Wax Paraffin

  NH2 Glycine Synthesis Oxoacetic Acid Carboxylic Acid Glyoxylic Acid Glycin Oxime Vinegar Acetate

  Emerging therapeutic potential of glycine in cardiometabolic diseases: dual benefits in lipid and glucose metabolism

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198663/

  ..

  Glycine is both an Amino Acid & Osmolyte

  Insulin & Glucagon Homeostasis

  getting really good results with the honey & vinegar test, its making something like Glycine, or a proto-amino acid compound.

  ..

  Glycine, serine, glutamine, and asparagine were associated with improved insulin sensitivity, whereas all other AAs were associated with decreased insulin sensitivity.

  Glutamate, tyrosine, isoleucine, and alanine had the largest effect on the reduction of insulin sensitivity.

  ..

  Prion Amyloid Type 3 Diabetes Lipid Peroxidation Lipotropic Osmolyte Methyl Doner

  Choline Betaine Inositol

  https://en.m.wikipedia.org/wiki/Type_3_diabetes

  https://en.m.wikipedia.org/wiki/Lipid_peroxidation

  https://en.m.wikipedia.org/wiki/Lipotropic

  Lipotropic Agent

  https://www.sciencedirect.com/topics/medicine-and-dentistry/lipotropic-agent

  ..

  the way Diabetes & Amyloid create a plaque barrer from dead cells, blocking nutrients.

  thats what the vinegar & honey is supposed to break up, by permeating, softening and via enzyme reactions desolove it.

  just fine tuning the raito, more like 50/50, the honey is the medicine, vinegar is the electricity.

  apparently 90% of Covid "loss of taste & smell" returns in 4 weeks, and 10% its permanent.

  the idea of vinegar & honey was to make Glycine & Betaine Osmolyte amino-acids, to help mitochondria heal & repair faster.

  not sure if it helped, or your just getting better at normal speed.

  covid appears connected to some kind of prion (spike) like HIV, triggering acceleration of amyloid plaque, causing neurodegeneration.

  antimalarial anticancer drugs possibly are effective because of microtubule pathways used to replicate, lock or bind parasites.

  my idea was some kind of mitochondria or DNA parasite called Plastid endosymbiont.

  an exotic Corallicolid Plastid may have been modified & fused with mycoplasma fermentans to make it contagious.

  this is unconfirmed, just my opinion.

  one thing i did find works is sea salt (electrolyte) in the vinegar honey kills candida & foot fungus almost instantly.

  nothing worked on my my one toe, for years, a couple drops of that stuff and it was gone.

  similar to how people use baking soda & sugar cancer cure, but a well rounded mineral complex works better, honey or sugar should be fine, but the vinegar puts lightning bolts in it.

  my problem with baking soda is the Sodium knocks out Potassium, causing Hypertension with me.

  what ive noticed, dont need much minerals with vinegar & honey, the vinegar seems to make them supercharged or monoatomic ions, meaning they absorb really well, just a pinch.

  apple cider vinegar is an acid, but acts like an alkaline, because the natural minerals from soil are supercharged.

  baking soda alkali seems to just neutralize digestion & raise sodium levels.

  Plastid is an algae cell that lives as an symbiont in other lifeforms, usually helping as a kind of extremophile metabolism function, but in the wrong species becomes parasitic living within mitochondria & bone marrow, making toxic acids.

  operating very similar to Candida.

  and the key element thatvis used to make toxic acids is Phosphorus, which is very important for biological functions, but if misfolded incorrectly makes amyloid plaque by prion proteins.

  its strange that the right kind of sugars are so beneficial for lipid & carbohydrate metabolism, meaning plaque.

  with the vinegar & minerals alone it was helping against Candida, but was too hot, but with the honey & less minerals seems the right balance, can drink it more often without the hot side effects.

  testing oversaturated vinegar with too much honey & minerals does appear to kill fungus & parasites via microtubules, but seems to slow down metabolism, meaning the acetic or citric acids need to be higher or high enough for the body to metabolize easily.

  suspension is Acetylation with Calcium Magnesium causes Dephosphorylation of Prion.

  ..

  Phosphorylation

  Polymerization of Fabrinogen

  Fibronectin Phospholipid

  Phosphorus Sulphur Sodum Tin

  https://en.m.wikipedia.org/wiki/Phosphorus_pentasulfide

  https://en.m.wikipedia.org/wiki/Sodium_dithionite

  https://en.m.wikipedia.org/wiki/Nickel_tetracarbonyl

  Prebiotic chemistry: a review of nucleoside phosphorylation and polymerization

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832566/

  Sources, essentiality and toxicological profile of nickel

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985085/

  ..

  GPI (Inositol) Glycosylphosphatidylinositol

  DSPC (Choline) Distearoylphosphatidylcholine

  PI Phosphatidylinositol

  PC Phosphatidylcholine

  ..

  https://en.m.wikipedia.org/wiki/Distearoylphosphatidylcholine

  https://en.m.wikipedia.org/wiki/Phosphatidylcholine

  https://en.m.wikipedia.org/wiki/Lipotropic

  ..

  Lipotropic compounds are those that help catalyse the breakdown of fat during metabolism. Without lipotropics, such as choline and inositol, fats and bile can become trapped in the liver, causing severe problems such as cirrhosis and blocking fat metabolism.

  ..

  Anti – Prion Systems in Yeast and inositol polyphosphates

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321833/

  Kinetics of the glucose/glycine Maillard reaction pathways: influences of pH and reactant initial concentrations

  https://www.sciencedirect.com/science/article/abs/pii/S0308814604006077

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• 
  @mikewick77(49)· 779d

  

  Ole Molly Tea Osmolyte O Smolyte O Smo Lyte O Small LIte Old Small Light

  ..

  Deep-sea osmolyte finds applications in molecular machines

  https://www.asiaresearchnews.com/content/deep-sea-osmolyte-finds-applications-molecular-machines-0

  Sequence-based identification of inositol monophosphatase-like histidinol-phosphate phosphatases (HisN) in Corynebacterium glutamicum, Actinobacteria, and beyond

  https://bmcmicrobiol.biomedcentral.com/articles/10.1186/s12866-017-1069-4

  ..

  Histidinol-Phosphate Phosphatase (HolPase)

  Inositol Monophosphatase (IMPase)

  Glycosylphosphatidylinositol

  The eighth step of L-histidine biosynthesis is carried out by an enzyme called histidinol-phosphate phosphatase (HolPase). Three unrelated HolPase families are known so far. Two of them are well studied: HAD-type HolPases known from Gammaproteobacteria like Escherichia coli or Salmonella enterica and PHP-type HolPases known from yeast and Firmicutes like Bacillus subtilis.

  However, the third family of HolPases, the inositol monophosphatase (IMPase)-like HolPases, present in Actinobacteria like Corynebacterium glutamicum (HisN) and plants, are poorly characterized. Moreover, there exist several IMPase-like proteins in bacteria (e.g. CysQ, ImpA, and SuhB) which are very similar to HisN but most likely do not participate in L-histidine biosynthesis.

  ..

  (TMA) Trimethylamine

  (TMAO) Trimethylamine N-Oxide

  (TMAU) Trimethylaminuria

  (TOR) Trimethylamine N-Oxide Reductase

  (CYT-C) Cytochrome Complex

  (FMO3) Flavin Monooxygenase 3

  ..

  Implication of Trimethylamine N-Oxide (TMAO) in Disease: Potential Biomarker or New Therapeutic Target

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213249/

  Methionine Metabolism: Key Enzymes, Reactions, and Interplay with Cellular Pathways

  https://www.creative-proteomics.com/blog/index.php/understanding-methionine-metabolism/

  Sink into the Epigenome: Histones as repositories that influence cellular metabolism

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109460/

  Glycoside vs. Aglycon: The Role of Glycosidic Residue in Biological Activity

  https://link.springer.com/referenceworkentry/10.1007/978-3-540-30429-6_67

  Unforeseen crystal forms of the natural osmolyte floridoside

  https://www.nature.com/articles/s42004-020-00376-z

  Glycation Damage: A Possible Hub for Major Pathophysiological Disorders and Aging

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147582/

  Current Methods for the Characterization of O-Glycans

  https://pubs.acs.org/doi/10.1021/acs.jproteome.0c00435

  Iminosugars: A host-targeted approach to combat Flaviviridae infections

  https://www.sciencedirect.com/science/article/pii/S0166354220302953

  ..

  Methionine synthase transfers a methyl group from 5-methyl-tetra-hydro-folate to homocysteine, yielding methionine and tetra-hydro-folate.

  Choline, a trimethylamine-containing compound and part of the head group of phosphatidylcholine, is metabolized by gut microbiota to produce an intermediate compound known as trimethylamine (TMA). TMA is rapidly further oxidized by hepatic flavin mono-oxygenases to form trimethylamine N-oxide (TMAO).

  ..

  Methyl Doner Osmolyte

  Glucagon

  CHARM Coupled Histone Autoinhibition Release Methyltransferase

  [Sulfur Toxicity] Hyperhomocysteinemia Methyl-Hydrogen-Folate MTHFR Methionine Homocysteine Cysteine Choline Betaine Methylamine Trimethylamine Trimethylaminuria [Nitrogen Toxicity]

  Cysteine & Choline the point between two oppsite spectrum of gene disorders, enzyme one-carbon metabolism malfunction.

  Trimethylaminuria is a rare problem, in comparison to MTHFR Hyperhomocysteinemia.

  in the center balanced is some kind of Osmolyte molecule, universal enzyme, stem cell tonic, telomere booster.

  ..

  DNA Methyltransferase Homocysteine (HCY) S-Adenosyl Homocysteine (SAH)

  (SAH) Bisulfide Sulfane Sulfanyl Butyrate Butter

  Vinegar Hydrogen Acetate Methane Carboxylate Ethylic Acid Ethanoic Acid

  Honey Monosaccharides Fructose Glucose

  Enzyme Hydrolysis Glycogenolysis Glycoprotein Glucagon Glycation Glycosyl Glycerol Glycoside Glycosidase Aglycone Osmolyte

  Glycosides can be activated by enzyme hydrolysis, which causes the sugar part to be broken off, making the chemical available for use.

  Aglycone-fed mice displayed strong autophagic reactions, mTOR regulation, and reduced plaque deposits and ß-amyloid levels.

  ..

  Formate Dehydrogenase FDH Floridoside Trehalose

  ..

  [Sulfur Toxicity] Hyperhomocysteinemia

  [Nitrogen Toxicity] Trimethylaminuria

  both extrems of Osmolyte malfunction, yet Sulfur being Spike (Prion).

  S-Glycoprotein Spike (Prion) = Sulfur

  Heparan Sulfate

  to undo this prion binding..

  Osmolyte Oxymel Glycoside Glycone Aglycone

  Glycosidic Bond:

  O- Oxygen S- Sulfur N- Nitrogen C- Carbon

  Glucuronic Acid Glucuronidation Glycoside Hydrolases Glycosynthases Glucuronidases Glucuronoside Glucuronide

  Extracellular Polymeric Substance (EPS)

  ..

  O-Linked Glycosylation O-Glycan O-GalNAc

  Osmolyte O-Smolyte O-Smalyte

  O-(Oxygen) Glycan Hydroxyl Group Serine Hreonine Tyrosine

  ..

  Glycans are attached to proteins in four different ways

  N-linked to asparagine (Asn),

  O-linked to the hydroxyl groups of serine (Ser), threonine (Thr) or tyrosine (Tyr),

  C-linked to tryptophan S-linked ..

  ..

  Functional Group

  O-Glycan Osmolyte Oxymel

  Carboxylic Acid (COOH) Methylene Group (CH2)

  Oxygen Glycan Acetylation

  O-Glycan O-Linked Glycosylation O-GlcNAcylation O-GlcNAc

  O-GlcNAc Transferase O-GlcNAcase

  ..

  Sugar Acid

  Aldonic Acid Aldaric Acid Ulosonic Acid Uronic Acid Glyceric Acid Gluconic Acid

  Acidic Acid Sugar Protecting Groups -OH Monosaccharide Carboxyl Glycoside
  Glycosyl

  ..

  Prion Glycoprotein Glycosylphosphatidylinositol C-terminus Myelination Myelin

  Proteases Enzymes Aldosterone

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• 
  @mikewick77(49)· 787d

  Deputized Zones

  Deputy ID # Picture Criminal Record Background Check BLOCKCHAINED

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• 
  @mikewick77(49)· 793d

  Using CRISPR to edit coral

  https://medium.com/scope-stanford-medicine/using-crispr-to-edit-coral-8dd3b6217cf9

  the red & green colors have more to do with the algae then the coral itself, meaning this new definition Corallicolid.

  Corallicolid Plastid is a Malaria symbiont that lives inside the coral.

  sounds like they are fiddling with that part.

  when the pH (hydrogen acids) become low (acidic) the symbionts will leave the coral reef & look for another location, causing bleaching.

  makes me wonder if this was used to manufacture disease, a clue?

  ..

  Cerebral (Brain) Organoid

  Cerebral organoids as a new model for prion disease

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294539/

  “Archealization” of human brain organoids

  https://www.nature.com/articles/s41386-021-01133-z

  ..

  pretty sure they are using some kind of Slime Mold or Corallicolid fused with human brain tissue, with some kind of immortal protein of Prion.

  Physarum Polycephalum

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• 
  @mikewick77(49)· 808d

  problem is trying to simplify my personal recipe, for someone else to duplicate, who dosnt have all the ingredients, so i should just explain my own recipe.

  vinegar (apple cider 32 oz)

  multi mineral complex (tablespoon)

  sea salt (teaspoon)

  niacin (teaspoon)

  msm (teaspoon)

  raw honey (tablespoon)

  probiotics

  coconut oil vegetable glycerin

  minerals & salt add little at a time as it expands via acid/base reactions.

  got to leave the vinegar lid loose for a week or so, as it finishes fermentation & expanding.

  coconut & vegetable glycerin, what does not desolve forms at the top, after fermentation, pour the top oil off.

  in my opinion, niacin & msm cover all the b vitamins.

  then a shot of that in the Fulvic/Humic acid, is my current setup, and it works.

  the approach is different then vitamin or supplement, its not to give any specific nutritional benefit, but specifically to break up toxic blockages via enzymes activators, then vitamins can actually work.

  the charged ions slow down parasitic microbes, and speed up natural immunity.

  slows down parasitic microbes via microtubule gateways & parhways, our biology being much larger is faster at processing ions.

  it kind of like making Chloroquine, Ivermectin, Fenbendazole, Suramin, Allicin, Methylene Blue & Betaine, by just using Vinegar, Honey, Sea Salt, Glycerol, Niacin & MSM

  to duplicate them all, using raw materials, and allowing the body to manufacture the correct outcome.

  with the honey, i also add premo probiotics to it, mix it in, and the vinegar does ferment along the way, to complete the complex Carbon elements.

  the body requires nitrogen & sulfur for carbon carbohydrate metabolism, yet requires vinegar to kickstart the enzyme reactions.

  nitrogen sulfur at equal amounts, the vinegar with a little extra minerals & raw honey.

  Glycerol CH3 Methyl Doner keeps the nitrogen from getting hot, protecting kidneys & DNA.

  Non-Flush Niacin, Thiamine, MSM, DMSO, Betaine, Inositol

  Glycerol Vinegar Diacylglycerol Oil

  ..

  been tucking away most ideas, until the picture locks in place.

  the cure to disease & parasites, chemistry sure does look like location of the mitochondria that heals & protects DNA.

  its almost like disease is locking the same enzymes that metabolize vitamins in cells.

  its difficult to explain, but all of the most powerful medications, for all kinds of diseases, look like the same mitochondria enzime lock, that determines health & sickness.

  its like disease is a mitochondria symbiont hyjacking the enzyme reactions of one very specific spot.

  testing Thiamine for a few months, and the conclusion is very close, but something missing to get all the enzyme moving along.

  the chemistry is so complex at this location, trying to simplify the exact vitamins & enzyme activators.

  unlocking the enzymes is the key.

  ..

  what i found interesting is the series of enzyme locks, a repeating pattern at the same locations across so many diseases.

  all seeming dependant upon one-carbon metabolism, locks all the other vitamins into toxins.

  so far, the only thing that seems to work is..

  Niacin with Inositol so to offer methyl CH3, MSM, Mineral complex for metalloenzyme reactions.

  and the only thing that seems to activate this is by putting all of them in vinegar.

  for some reason the Nitrogen & Sulfur act as a zipper, unzipping toxic acid buildup.

  been trying to specify target things like Mycoplasma Fermentans (Incognitus) & Prion Amyloidosis.

  recently noticed the Vinegar & Niacin (Inositol/Betaine) idea is similar to Creatine, (methylguanidine-acetic acid).

  from what i can figure, its some kind of synthetic mycoplasma bound to a symbiont Alopaecia, causing so much chronic diseases?

  and like what you say, the toxic foods & pesticides, but thats also similar toxins these microbes produce, inside mitochondria.

  im no longer trying to kill, but more like focus upon the very exact microtubule pathways & binding mechanics.

  Prion for example, match exactly what it wants, except bound to minerals ions that will ultimately make it slower then the bodys immunity, bind & swell it up until the immunity can recognize it.

  mycoplasma for another example, has to more do with Lipids, making them toxic, so by enzymes breaking down the toxic acid buildup, then eventually it will break down the Lipid membrane of the mycoplasma.

  well, not use any kind of actual medication, poison or antibiotic, but to use enzymes, mineral ions, to slow & swell the critters, so becoming resistant to treatment is impossible, because the molecular binding is smaller then the target.

  ..

  it almost seems as if Osmolyte Mythyl Donor is the nitrogen with sugar alcohol with the vinegar that can carry the mineral ions into parasitic microbes.

  parasitic yeast & bacteria seem to use Glyceric Acid or Glycolipids without Nitrogen, so do extremophiles, similar to antifreeze.

  mitochondria parasites may be responsible for immortal cell rewriting of misfolded telomeres.

  the Vinegar & Honey are giving interesting results, all this time never understood the secret of enzyme reactions.

  Metalloprotease Metalloenzyme

  vs

  Osmolyte Methyl Doner

  which is more important per ratio, salts or carbohydrates, to be broken down with vinegar into simplest compounds?

  im beginning to see how its the complex carboxylates, and less salts.

  ..

  vinegar, honey & glycine.

  seems stupid simplistic, but its doing something beyond what science has figured out.

  reading through the data, had to make my own conclusions.

  Naturally occurring osmolytes are one of the most potent stabilizers for many proteins and are capable of reversing protein misfolding and/or aggregation, which are known to be underlying cause of several diseases.

  tried all the Niacin, Thiamine, Betaine, DMSO, Mineral Ion combinations, all that stuff, and it was working alright, but this new snake oil lit all that that stuff up, literally, it triggered all the Nitrogen accumulated in my kidney & liver, triggered all kind of enzyme reactions, good luck going to sleep testing that stuff, up all nigjt buzzing with energy, from 8 hours after taking a shot.

  vinegar, honey, vegetable glycerin, mixed in a cup of water to delute.

  searched this combination of ideas on Twitter, dosnt seem to publicly aware of this, so if you can get an understanding of the general idea, you will be ahead of the curve, even the papers dont exactly know why osmolytes unfold misfolded proteins.

  matched up the most effective osmolytes into a list, looking at the chemistry for repeating patterns, more clues.

  two of the most unique & powerful osmolytes are nearly identical to Thiamine, when put together.

  Trigonelline (Nitrogen)

  Dimethylsulfoniopropionate (DMSP / Sulfur)

  and basically what its doing is going into the backbone of protein via amino acid reconstitution, because its smaller then the molecule itself, unfolds it & makes it viable again.

  Methyl Doner CH3 is not a Nitrogen, but a Carbon & Hydrogen reaction, the reason its so effective, is because Hydrogen (Proton) is the smallest atom, and can pedetrate any other molecule compound bonds, and reshape the foundation from the core or backbone.

  oh, and ..

  Osmolyte & Methyl Doner CH3 are basically the same thing, interchangeable idea.

  Glycerol or Acetate alone does nothing, together is called Glycerine acetate, usad as a fuel addictive, it does nothing, it seems to require other "things" to make the enzymes continue operating, specially when a chemical lock occurs.

  this is why honey & minerals comes to play.

  Honey offers complex Organic Acids.

  Minerals help Metalloenzyme operations.

  Metalloprotease Metalloenzyme

  vs

  Osmolyte Methyl Doner

  which is more important per ratio, salts or carbohydrates, to be broken down with vinegar into simplest compounds?

  im beginning to see how its the complex carboxylates, and less salts.

  another conclusion is that while Nitrogen, Sulfur & other elements are required to cascade enzyme reactions, we already have enough from food, gut & liver reserves.

  excess Niacin, Thiamine or MSM may enhance the reactions, but may not be critical as the other three ingredients put together.

  the Vinegar & Glycerol is very potent, even without adding all the other things, very little required of the extras.

  seems to trigger the similar reactions as high dose Thiamine.

  way too much honey, without time to ferment down, is probably not a great idea, seems to spike blood sugar in funny ways.

  Creatine & Osmolyte are not attributed to a cure to any chronic disease, nor is niacin, vinegar, or minerals.. none of it.

  everything needs to be triangulated, to a very specific point, meaning the same cure to LYME, HIV, Prion ect.. all the most terrible diseases, they have something in common that science is not able to explain.

  the way Thiamine & Ivermectin are insecticides, reminds me of this Osmolyte pathway, Salt/Sugar with a Nitrogen, insect draws blood & it begins to ferment & manufacture Carbon Diox & Nitrogen Oxide, which is good for mammal Vascular systems, and not for Invertebrate.

  this is the same explanation to explain how mitochondria parasites swell & become paralyzed for immune system identification.

  ..

  getting mixed feedback regarding Methylene Blue & DMSO being toxic, likely because of the Sulfur.

  this article talks about Glycerol being used as a non-toxic alternative for DMSO for Cryogenic applications, meaning it can likely be an absorbent in a similar way.

  and capable of refolding proteins from the hydrogen backbone from salt ions, polyol from proto fatty acids & lipid formation.

  dont exactly know how to do this trick yet, its obviously not just Creatine, or Glycerol, but it something in that direction.

  needs..

  Polyol Nitrogen Minerals

  Osmolyte Methylamines Inorganic Ions

  whats fascinating is the Polyol Sugar Alcohol & Inorganic Ions are dependent upon each other to pH balance the Osmolyte Pathway.

  together they manufacture Amino Acids, Enzymes, Proteins, Fatty Acids & Lipids.

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• 
  @mikewick77(49)· 811d

  

  

  B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review

  https://www.mdpi.com/2072-6643/8/2/68

  The inter-related contribution of the B vitamins to the citric acid cycle and electron transport chain, the central catabolic process in mitochondria

  Acetate (Acetic) Acetyl-CoA Acetylcholine
  Choline Betaine Pyruvate Enzyme CoA Acetyl CoA

  Histone Acetylation Amyloid

  ..

  Acetate Revisited: A Key Biomolecule at the Nexus of Metabolism, Epigenetics and Oncogenesis—Part 1: Acetyl-CoA, Acetogenesis and Acyl-CoA Short-Chain Synthetases

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689297/

  plasma acetate levels are higher in young adults (average 170 micromolar) than in adults aged 40 to 57 (average 130 micromolar).

  ..

  Folic vs Folate B12 Synthetic

  this may be another reason for the B vitamin lock.

  they use Glyphosate with synthetic B vitamins on the same grain, and call it ADHD & Genetic Disease.

  ..

  Elevated homocysteine levels in human immunodeficiency virus-infected patients under antiretroviral therapy: A meta-analysis

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419119/

  A Case-Control Study of the MTHFR C665T Gene Polymorphism on Macrocytic Anemia Among HIV-Infected Patients Receiving Zidovudine

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346408/

  ..

  https://www.healthline.com/nutrition/chelated-minerals#types

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• 
  @mikewick77(49)· 840d

  Dopamine Dopaminergic Phosphorus Phosphate Retinoid Retinyl Esters Retinol Retinal Liver

  Dopaminergic Pathways

  https://en.m.wikipedia.org/wiki/Dopaminergic_pathways

  Retinoids in the Pathogenesis and Treatment of Liver Diseases

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002467/

  Retinoid X Receptor: Cellular and Biochemical Roles of Nuclear Receptor with a Focus on Neuropathological Involvement

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015987/

  ..

  it seems to be the outcome of all the different diseases, because it locks immunity.

  immune suppressing microbes.

  locks everything up.

  specifically the Phosphorus, which is required for everything else to work.

  things like Glyphosate & parasites ferment toxic Phosphate binding compounds, making what is vital into toxic waste.

  ..

  Retinoid Receptor Retinoic Acid Receptor Retinoid X Receptor Retinoid X Receptor Alpha Retinoid X Receptor Beta Retinoid X Receptor Gamma
  Liver X Receptor Related Orphan Receptor

  https://en.m.wikipedia.org/wiki/Retinoid_receptor

  https://en.m.wikipedia.org/wiki/Retinoic_acid_receptor

  https://en.m.wikipedia.org/wiki/Retinoid_X_receptor

  https://en.m.wikipedia.org/wiki/Retinoid_X_receptor_alpha

  https://en.m.wikipedia.org/wiki/Retinoid_X_receptor_beta

  https://en.m.wikipedia.org/wiki/Retinoid_X_receptor_gamma

  https://en.m.wikipedia.org/wiki/Liver_X_receptor

  https://en.m.wikipedia.org/wiki/RAR-related_orphan_receptor

  ..

  testing my most recent idea, NAC, Castor Oil & Sea Salt.

  its supposed to just get the enzymes moving along.

  possibly some charcoal at different times to help detox.

  every chronic disease seems to stem from Vitamin A Retinoid locked up, from toxic Phosphate lipids.

  from pathogens to Glyphosate, liver & immune system locked from natural immunity.

  after doing this little protocol, i began having dreams again, every night, and every nap, for weeks now.

  what NAC seems to be doing is B & C Vitamins, the Castor keeps the enzymes moving along vis Methylation of Hydrogen, the Sea Salt are the Metalloenzymes.

  everything is enzyme related, disease is blocked enzymes, gene knock-out.. enzyme locked.

  and raw honey.

  ..

  so everything is still pointing to caramelization of sugar, lemon, oil, sea salt, plus Nitrogen & Sulfur.

  everything seems dependent upon the phosphate orientation, just not exactly sure how.

  Lysine & Carnitine is also NAC, metabolize lipids in mitochondria.

  so maybe breaks up the wrong forms of Phosphorus?

  seems like anything that can break down Dioxins & PFAS forever chemicals, will break down toxic acid sludge from the body, specially Salt Bile Metalloenzyme & Nitrogen (Protease Enzymes).

  Fulvic Humic acid, going to spike it with enzyme activators, Castor oil & sea salt.

  this was the original plan 4 years ago, but tried to make my own Fulvic via Hemp seed fermentation, and it went bad, so the idea kind of got left in the dust.

  caramelization of plant biomass & honey was along the same idea, for the enzymes to complete the breakdown process, every element needs to be available in its most monoatomic state, so the toxins reassembly binding is neutralized.

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• 
  @mikewick77(49)· 847d

  

  

  Lipid Unsaturated Oil Triglyceride Fatty Acid PUFAs Methyl Group CH3

  Fatty Acids Composition of Vegetable Oils and Its Contribution to Dietary Energy Intake and Dependence of Cardiovascular Mortality on Dietary Intake of Fatty Acids

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490476/

  PUFAs depending on the position of the first double bond from the fatty acid methyl-end. The human body cannot synthesize PUFAs with the first double bond on C3 and C6 from the methyl-end because of the absence of appropriate enzymes.

  ..

  Methyl Group CH3 seems to be the exact point of disruption, from good to bad reactions.

  meaning, this is how & where Vitamin A & Phosphorus lock the liver from processing, the very beginning of the enzyme chain reactions.. locked, and toxic acid overload & disease.

  all disease seem to target the Lipids.

  my suspension is that Niacin alone binds the Methyl CH3 from the remaining pool, so not very helpful, yet (IHN) Inositol Hexa Nicotinate is supplied with enough CH3 to flip toxic lipids back, and looking at CH3 in comparison to unsaturated Triglyceride, it appears to be the same general compound as CH3, or close enough to assist the lipid flipping.

  this idea goes along what Garth was trying to do, with Lipid Replacement Therapy & Hydrogen Water Treatment.

  unfortunately both of those are only therapeutic, what im trying is a cure, because as the lipids flip, eventually they will find the source of the disease, and kill it.

  ..

  B Vitamins (Nitrogen/Sulphur) & C Vitamins (Citric), Essential Minerals & Castor or Olive Oil.

  anything that can trigger "enzyme activator" reactions, to clear Vitamins A & Phosphorus blockages in liver, kidneys, gall bladder, bile duct.

  the idea is, the body has the ability to handle any kind of disease, but the toxic acid parasitic fermentation & toxic pesticides block the enzyme process, locking immune system.

  the viral diseases seem to be some kind of mitochondria parasite, that are capable of evolving to medications, only an active immune system is powerful enough to keep at bay.

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• 
  @mikewick77(49)· 856d

  The Last of Us: Ophiocordyceps

  how exactly does a Super-Prion event infect the entire world?

  in ancient past, before vaccines, how did it spread so effectively?

  insects, birds, fungus, comets?

  is this global temperature rising & fungus mutation fact or fiction hypothesis? and any connection to Super-Prion events?

  ..

  Do Amyloids Remember Their Origin? New Insights into the Prion Species Barrier

  https://www.cell.com/fulltext/S1097-2765(04)00208-4

  Extrapolation of these data to the mammalian systems represents a new major breakthrough, further underlining the similarities between yeast and mammalian prions.

  ..

  The recent identification of a bacterial prion-forming protein suggests that bacteria also harbor prions.

  prion-like proteins are involved in the interaction between phages and bacterial cells and postulate the possible association of prion-like domains with human diseases

  ..

  the chemical that triggers a bunch of problems regarding yeast fungus toxins have to do with Vitamin A, flipped to the unusable form, builds up & lockes all other nutrients, only B Vitamins, Heterocyclic Compounds using Nitrogen & Sulfur & Triglyceride can unlock this enzyme lock.

  Inositol is the part to make Niacin Non-Flush, by acting as CH3, it protects the liver from Methylation binding.

  the MSM with Castor seemed to just make me sleepy, im really having good results with the Inositol Nicotinate & Castor.

  looking threw comments of people experience with it & says keeps away the voices in severe schizophrenia.

  the Inositol is non toxic to dogs & cats, and has neuroprotective properties, and calm OCD symptoms.

  been testing IHN & NAC, with. a little shot of Castor. i think its behaving like Lipid Replacement Therapy, and it turns the Castor into the equivalent of Vitamin E antioxidant properties.

  tried every different kind of combination, with everything else, its ultimately the Nitrogen to Sulfur, leaning towards more Nitrogen, with that special sugar alcohol CH3 Group, and unsaturated Triglyceride.

  the Nitrogen & Sulfur is two sides of the enzyme zipper, the oil is the zipper flap that pulls it, and the special sugar protects the DNA from the enzyme reactions.

  the minerals are part of the equation, but probably got enough of them, but if electrolytes are low, it would probably stop working as well.

  took the Castor, Nician, NAC & Minerals today, first time trying with the Minerals in this combination.

  for whatever reason, having tried this combination yet, see if it feels any different, cause normally the minerals dont seem to digest or dissolve all the way, is how the vinegar idea came along.

  but the stomach acids can do the vinegar part all by itself, but with the other vitamins should actually do what its supposed to do, make enzymes.

  any other combination would stop working over time, the enzymes reactions would stop, and i need them moving.

  i suspect the toxic bile acids collect into bad phosphate like glyphosate in the liver & kidneys, and phosphorus needs to be triggered by good enzymes to make good protein & lipids.

  and all of this is dependent upon the Protective Group in the Nician & NAC.

  NAC = Acetyl iHN = Inositol

  and if all of this is correct, and works the way i think its working, it will convert the toxic phosphorus buildup into all the other vitamins along the chain.

  meaning it will make Vitamin A, B1, B6, B9, B12, Vitamin C, Vitamin E & D.

  vitamin B3 has a simpler structure then B1, makes me wonder if the numbers are mixed up, regarding the way they metabolize into other Enzymes, an even possibility into other vitamins via Heterocycle assembling, and even the water to oil solubility because of the Sulfur.

  that second picture, see how Phosphorus is insoluble with minerals, that the part that gets toxic & blocked up, and needs to be unbound to make the other B vitamins function.

  and all of this is because of Vitamin A being locked into a toxic form of acid, that also requires B vitamins to unlock.

  Vitamin A & Phosphorus get locked & only the B Vitamins with a small amount of Sulfur, unsaturated Oils & Minerals can unlock.

  the good Carbon & Hydrogen elements are the "Protective Groups".

  and the way i knew it was the right combination, was because my dreams came back almost instantly, vivid & clarity.

  ..

  the idea that by unlocking vitamin A will also unlock Phosphate from the liver & begin assembling all the restvof tye vitamins & fix the toxic acid buildup, that mycoplasma & cancer produces, and possibly a cure as well.

  that old fella who discovered B1 was reversing genetic diseases, that was a big clue for what im trying, looking through his papers, he was also struggling with how eventually it stips working, and thats what im trying to figure out.

  they discovered it was directly to do with Vitamin A & Phosphorus lock.

  overall, the chemistry is damn near identical to Fenbendazole, Castor & Pine Terpinene.

  The Terpinene is acting as the "CH3 Protective Group".

  people with diabetes or dialysis cant have Phosphorus, Potassium or Vitamin A.

  im almost assuming that Menthyl Nicotinate & Inositol Nicotinate will be the result of Niacin, Carbohydrate & Triglyceride.

  meaning that Nician (Nitrogen) with an Oil & Sugar will ultimately be the same thing.

  not sure how that will work out in real world application, testing the regular hot Nician together with Sugar & Oil?

  ..

  CH3 Methyl Group Acetyl vs Acetal

  https://wikidiff.com/acetyl/acetal

  https://en.m.wikipedia.org/wiki/Methyl_group

  Methyl vs Menthyl

  Phytogenic biosynthesis and emission of methyl acetate

  https://onlinelibrary.wiley.com/doi/10.1111/pce.12164

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• 
  @mikewick77(49)· 858d

  Neurotransmitter Serotonin B12 GABA Dopamine Folate Methylation Biosynthesis Bioactivation DNA Synthesis B Vitamins Thiamine Niacin Heterocyclic Heterocycle Heteroatom Gene Mutation Serine Metabolism Serine Synthesis Pathway (SSP) PHGDH (gene) MTHFR (gene) Methyl / Folate SAM Cycling Lipid Metabolism Triglyceride Polymorphism Plasmid Plastid Protist Phage P53 C677T

  B Vitamins and the Brain: Mechanisms, Dose and Efficacy

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772032/

  B Vitamins in the nervous system:

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930825/

  Folate and DNA Methylation:

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262611/

  ..

  PHGDH and its inhibitors for regulating cancer metabolism

  Emerging evidence suggests that cancer metabolism is closely associated to the serine biosynthesis pathway (SSP), in which glycolytic intermediate 3-phosphoglycerate is converted to serine through a three-step enzymatic transformation. As the rate-limiting enzyme in the first step of SSP, phosphoglycerate dehydrogenase (PHGDH) is overexpressed in various diseases, especially in cancer.

  ..

  MTHFR (gene)

  Methylenetetrahydrofolate reductase deficiency

  Methylenetetrahydrofolate reductase (MTHFR) is the rate-limiting enzyme in the methyl cycle, and it is encoded by the MTHFR gene.

  Methylenetetrahydrofolate reductase deficiency is the most common genetic cause of elevated serum levels of homocysteine (hyperhomocysteinemia). It is caused by genetic defects in MTHFR, which is an important enzyme in the methyl cycle.

  ..

  Methylenetetrahydrofolate (MTHFR), the One-Carbon Cycle, and Cardiovascular Risks

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703276/

  Allosteric inhibition of MTHFR prevents futile SAM cycling and maintains nucleotide pools in one-carbon metabolism

  https://www.jbc.org/article/S0021-9258(17)50430-5/fulltext

  Methylenetetrahydrofolate reductase and psychiatric diseases

  https://www.nature.com/articles/s41398-018-0276-6

  One-Carbon and Polyamine Metabolism as Cancer Therapy Targets

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775183/

  Is the MTHFR C677T variant a genetic risk factor in the etiology of autism spectrum disorder? Is it alone or by combined with rare variants of the PHGDH gene? Running Title: Is the MTHFR C677T a genetic risk factor for autism?

  https://www.bibliomed.org/?mno=85003

  Nutrigenomics and Nutrigenetics

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481686/

  ..

  Pyrethroid

  Developmentally exposed mice had disruptions in 116 metabolites which clustered into pathways for folate biosynthesis, retinol metabolism, and tryptophan metabolism.

  ..

  What The Science Says About B3 Vitamins And Methylation

  https://www.aboutnad.com/scientific-analysis/what-the-science-says-about-b3-vitamins-and-methylation

  Emerging Role of Nicotinamide Riboside in Health and Diseases

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9571518/

  ..

  Nicotinamide Riboside Inositol Nicotinate

  Simple Sugar:

  Ribose Inositol Mannitol

  ..

  Sirtuin

  Sirtuin activators and inhibitors: Promises, achievements, and challenges

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342514/

  The SIRT6 activators bind, independent from substrate, to the acyl channel and might induce an enzyme conformation with increased substrate peptide affinity as suggested by such kinetic effects of free fatty acids, which are assumed to also bind to the acyl channel

  ..

  Role of Sirtuins in Retinal Function Under Basal Conditions https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276360/

  NAD+ and sirtuins in retinal degenerative diseases: a look at future therapies

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235699/

  Implications of NAD+ Metabolism in the Aging Retina and Retinal Degeneration

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238357/

  SIRT1, a histone deacetylase, regulates prion protein-induced neuronal cell death

  https://www.sciencedirect.com/science/article/abs/pii/S0197458010003994?via%3Dihub

  Sirtuins and Their Roles in Brain Aging and Neurodegenerative Disorders

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357501/

  A neuroprotective role of SIRT1 has been also observed in prion diseases.

  ..

  i think one of the key goals is to get the Vitamin A flipped in the right direction, then the enzymes start working.

  seems everything depends upon enzyme unlocking, specially with Vitamin A.

  i dont think we need much A, but its the main malfunction that stops everything else.

  found papers explaining..

  B-Vitamins & NAC-Acetyl flip Retinol into Sirtuin.

  NAD is required to manufacture SIRT, but Niacin inhibits this process by stealing the Methylation OH from the liver, and requires a simple sugar to neutralize.

  Retinol toxicity is likely the dark pigments of Phosphorus, locked into toxic acids.

  Resveratrol from grapes have only Phenol, while grapes naturally have Nitrogen & Sulfur.

  Castor oil is allowing the simple B3 & B1 vitamins to morph into tue ither more complex B vitamins & Heterocycle compounds, drawing out the locked acid Phosphorus plaque from organs.

  Phosphorus Phosphate Polyphosphate Glyphosate

  Hypervitaminosis A  Retinoid Retinol Retinal Retinyl Retinaldehyde

  ..

  Efficacy and Safety of Inositol Hexa Nicotinate (IHN) in Improving Serum Lipid Profile in Patients with Low HDL Levels

  https://www.medicalandresearch.com/current_issue/1565

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• 
  @mikewick77(49)· 869d

  Niacin

  Pyridoxine

  Inositol Nicotinate

  ..

  Cicada Fungus Massospora Entomophthoraceae Zygomycota

  https://en.m.wikipedia.org/wiki/Zygomycota

  Trisporic acid is a C-18 terpenoid compound that is synthesized via β-carotene and retinol pathways in the zygomycetes.

  It is a pheromone compound responsible for sexual differentiation in those fungal species.

  ..

  Thiamine Inositol Nicotinate Pyridoxal Phosphate CD38

  https://en.m.wikipedia.org/wiki/Inositol_nicotinate

  https://en.m.wikipedia.org/wiki/Inositol

  https://en.m.wikipedia.org/wiki/Pyridoxal_phosphate

  https://en.m.wikipedia.org/wiki/CD38

  ..

  Indole Vitamin B14 Pyrroloquinoline Quinone

  https://valentinosnaturals.com/pqq-or-b14-what-is-this/

  https://valentinosnaturals.com/citicoline/

  ..

  Inositol

  Mannitol

  Riboflavin

  ..

  B Vitamins Indole Indole-3-Carbinol PQQ Fenbendazole

  Thiocyanate Diindolylmethane Allicin Melanin

  Vitamin B8: adenosine monophosphate (AMP), also known as adenylic acid. Vitamin B8 may also refer to inositol.

  Vitamin Bm: myo-inositol, also called "mouse antialopaecia factor".

  Alopecia areata is an autoimmune disease that attacks your body’s hair follicles, causing patchy hair loss.

  Alopecia Inositol Nicotinate

  The Biomedical Uses of Inositols: A Nutraceutical Approach to Metabolic Dysfunction in Aging and Neurodegenerative Diseases

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554709/

  Nature-inspired remodeling of (aza)indoles to meta-aminoaryl nicotinates for late-stage conjugation of vitamin B3 to (hetero)arylamines

  https://www.nature.com/articles/s41467-020-19610-2

  Synthesis of indoles

  https://en.m.wikipedia.org/wiki/B_vitamins

  ..

  Vitamin B14 PQQ Pyrroloquinoline Quinone Methoxatin Indole

  ..

  found an unusual link between Carbon, Nitrogen & Sulfur, its connections to B Vitamins, Allicin, Cannabinoids, Fenbendazole ect..

  how it may be possible to use something like B1, B3 & MSM Mannitol to bind via highly acidic stomach acids, to produce Indole like compounds.

  its almost impossible to explain, the chemistry "Cycles" are beyond difficult to track, the goal is using simple vitamin & supplements, to reach a very specific outcome.

  ..

  Exploring the Etiological Links behind Neurodegenerative Diseases: Inflammatory Cytokines and Bioactive Kynurenines

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177899/

  Picolinic Acid

  https://en.m.wikipedia.org/wiki/Picolinic_acid

  Pyridinecarboxylic Acida

  https://en.m.wikipedia.org/wiki/Pyridinecarboxylic_acids

  Sodium Thiosulfate

  https://en.m.wikipedia.org/wiki/Sodium_thiosulfate

  ..

  Vitamin A Metabolism:

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042718/

  Enzymatic Conversion of Proretinoid Carotenoid to Retinoid (Bcmo1)

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• 
  @mikewick77(49)· 879d

  

  

  

  https://en.m.wikipedia.org/wiki/Chloroplast#Starch_granules

  

  Pyrenoid Starch Granules Heterotrophic Microalgae

  Starch granules are very common in chloroplasts, and in some other plastids like amyloplasts.

  In red algae, starch granules are found in the cytoplasm rather than in the chloroplast.

  Starch granules are composed of two distinct glucose polymers - amylose and amylopectin. Amylose constitutes 5-35% of most natural starches and has a major influence over starch properties in foods. Its synthesis and storage occurs within the semicrystalline amylopectin matrix of starch granules.

  Cytoplasm Starch Granule Resistant Starch Amyloplast Amylose Prion Peptide Semi-Crystalline Amylopectin

  ..

  Prion Glycosylphosphatidylinositol p53

  https://en.m.wikipedia.org/wiki/Glycosylphosphatidylinositol

  https://en.m.wikipedia.org/wiki/P53

  ..

  The Multifaceted Functions of Prion Protein (PrPC) in Cancer

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605613/

  p53 amyloid aggregation in cancer: function, mechanism, and therapy

  https://ehoonline.biomedcentral.com/articles/10.1186/s40164-022-00317-7

  ..

  Prion Glycosylphosphatidylinositol

  Prion protein contains two N-linked glycosylation sites and a glycosylphosphatidylinositol (GPI) anchor.

  The large size of the N-linked sugars, together with their dynamic properties, enables them to shield two orthogonal faces of the protein almost completely. Thus, the sugars can protect large regions of the protein surface from proteases and from nonspecific protein−protein interactions.

  Immunoprecipitation of prion protein with calnexin suggests that in the ER the oligosaccharides may provide a route for protein folding via the calnexin pathway.

  Glycan analysis has shown that prion protein contains at least 52 different sugars, that these consist of a subset of brain sugars, and that there is site specific glycan processing.

  ..

  Oligosaccharide Oligonucleotide Glycoprotein

  Glycosylphosphatidylinositol

  malaria toxin .. glycosylphosphatidylinositol (GPI) anchor

  Synthesis and medical applications of oligosaccharides

  https://www.nature.com/articles/nature05819

  ..

  Methylglyoxal

  https://en.m.wikipedia.org/wiki/Methylglyoxal

  Role of Methylglyoxal in Alzheimer's Disease

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966409/

  ..

  A Case of Cellulitis Associated with Coral Injury

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4903982/

  i was told by a marine biologist, if Coral Reef is not completely removed from a cut, it will begin growing inside your body, onto the bone

  wonder if the prion inserts have anything in common with coral?

  ..

  Coral Spherulite Crystals

  Corals carefully organize proteins to form rock-hard skeletons

  https://www.sciencedaily.com/releases/2021/04/210408131455.htm

  Crystal nucleation and growth of spherulites demonstrated by coral skeletons and phase-field simulations

  https://www.sciencedirect.com/science/article/pii/S1742706120303573

  How do coral barnacles start their life in their hosts?

  https://royalsocietypublishing.org/doi/10.1098/rsbl.2016.0124

  ..

  Crystallization of Polymers

  https://en.m.wikipedia.org/wiki/Crystallization_of_polymers

  https://en.m.wikipedia.org/wiki/Zooxanthellae

  https://en.m.wikipedia.org/wiki/Pyrenoid

  https://en.m.wikipedia.org/wiki/Prototheca

  https://en.m.wikipedia.org/wiki/Algaemia

  Cnidarian Corals Jellyfish Sea Anemones Hydrozoans

  Sea Wasp

  https://en.m.wikipedia.org/wiki/Chironex_fleckeri

  https://en.m.wikipedia.org/wiki/Cnidocyte

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• 
  @mikewick77(49)· 884d

  NAC Thiamine

  Benefits of antioxidant supplementation in multi-trauma patients

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505376/

  Up-regulation of caveolin-1 and blood–brain barrier breakdown are attenuated by N-acetylcysteine in thiamine deficiency

  https://www.sciencedirect.com/science/article/abs/pii/S0197018610002792

  The effect of N-acetylcysteine on biofilms: Implications for the treatment of respiratory tract infections

  https://www.sciencedirect.com/science/article/pii/S095461111630141X

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• 
  @mikewick77(49)· 885d

  

  Mount Pinos Mount Rubidoux Jurupa Valley Gabrielino Tribe Serrano Tribe John Peabody Harrington

  https://en.m.wikipedia.org/wiki/Mount_Rubidoux

  https://en.m.wikipedia.org/wiki/Mount_Pinos

  https://en.m.wikipedia.org/wiki/Kizh

  https://en.m.wikipedia.org/wiki/Tongva

  https://en.m.wikipedia.org/wiki/Chumash_people

  ..

  theroy regarding Jesus 1000 years of peace, already happened, and this is why the entire world is literally fully loaded with greek like temple structures, star forts, ect...

  after the fall of Atlantis (Old Testament) everything was destroyed, then a crawling back into empires from the surviving (Sumerian).

  once they went back into full warfare & debauchery, Jesus was born, and promised to return shortly, and rule for 1000 years.

  rebuilding the world into a literal utopian riddled with mysterious coded buildings & libraries, then retreated back away once the time & requirements were completed.

  then some kind of Phoenix Rapture or sky event, this caused some kind of world mud flood, wheat & shaft & destroyed the unworthy to rebuild in the ruins.

  the devil has but a short time to rule until the final judgment.

  and the masonic Odd Fellows, Circuses, Bankers, Rothschild Nelphlim dragon hybrid bloodlines re-populated America with a breeding program, world fairs, cabbage patch orphans, railroads by Tartarian Chinese slaves ect..

  not to mention the quantum computer technology put deep within rhe earth energy grid points, to hyjack the true matrix, with a false one, an overly.

  ..

  not about the engine, its a particle accelerater, it opens up "things", its not an easy thing to explain.

  took me many years to figure out how the engine works, its like a ramjet, with multiple blast chambers, that would spin the combustion into a toroidal venturi chimney draw, then slowly incorporate water into the intake upwards, the top chamber will eventually build up an unusual cold gas element that would slowly move downward, pulling back in, creating a lightning storm effect, in the toroidal chamber.

  once this process has gone into full temperature, the ceramics will fuse into some kind of amorphous magnetic material, and will no longer require regular fuel.

  ..

  what about how the jews never wrote the Bible, but stole it, then re-wrote it, is why mythology mimics it.

  all the jews wrote was the Talmud.

  the ancient megalithic structures, biblical battles, them wernt jews.

  they took the history of a previous civilization, as there own.

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• 
  @mikewick77(49)· 886d

  Systemin is a plant peptide hormone involved in the wound response in the family Solanaceae. It was the first plant hormone that was proven to be a peptide.

  The receptor for systemin was first thought to be the same as the brassinolide receptor but this is now uncertain. The signal transduction processes that occur after the peptides bind are similar to the cytokine-mediated inflammatory immune response in animals.

  https://en.m.wikipedia.org/wiki/Plant_peptide_hormone

  https://en.m.wikipedia.org/wiki/Plant_defensin

  https://en.m.wikipedia.org/wiki/Systemin

  ..

  wonder if global warming fungus toxic mutation hypothesis & superprion pandemic, have anything in common?

  how can prion self assemble Tunnelling Nanotubes (TNTs) if its not a living "thing"?

  just seems similar to how a slime mold has a brain, without a brain, retains memory.

  so prion is.. self assembling, makes microtubules, a hydrogel, a spike protein, is nearly indestructible, airborne shedding & seems to have a brain without a brain?

  ..

  Synthetic Thioesters of Thiamine: Promising Tools for Slowing Progression of Neurodegenerative Diseases

  https://www.mdpi.com/1422-0067/24/14/11296

  Tunnelling nanotubes between neuronal and microglial cells allow bi-directional transfer of α-Synuclein and mitochondria

  https://www.nature.com/articles/s41419-023-05835-8

  Plastid transit peptides—where do they come from and where do they all belong? Multi-genome and pan-genomic assessment of chloroplast transit peptide evolution

  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456531/

  ..

  speculating on the evolution or origin of prion, regarding malaria apicoplast & plastid biogenesis.

  alga something infecting mitochondria, misfolding proteins, making prion peptide.

  meaning the definition of a virus as not alive is possibly outdated logic.

  just speculating on the evolution or origin of prion, regarding malaria apicoplast & plastid biogenesis.

  the alga endosymbiont (virus) requires mitochondria to habitat, otherwise goes dormant into spike-prion encapsulated seed or spore as self assembling hydrogel plaque, similar to bacteria biofilm.

  this unusual extremophile plastid (mitochondria alga) weaponized with gmo mycoplasma fermentans, renamed a bacterial plasmid, goes dormant in any environment besides bone marrow or mitochondria, manufacturing spike spores to reinfect other cells, and mislabeled the replication as a non living virus.

  one of the biggest clues is how the metabolism & enzyme activators flip both carbohydrates & lipids.

  thats the most important part of all disease, parasites, genetic disorders, and everything else.

  unusual symptoms of taking B1 & NAC, sometimes with Vitamin-C, MSM & Minerals, specially including Magnesium & Molybdenum.

  the first few days is a cold feeling, about the 4th day is a warm feeling, as the enzymes go into the next phase, ear ringing, head pressure, flushing, agitation, aches in old injuries, skin smoothness, fungus infection inflammation into itchy, yet going away.

  articles regarding NAC against Candida.

  its making my 30 year old feet problem stop peeling, yet its still itchy, almost like a healing itch.

  i dont know if its an absolute remedy yet, but something different is happening.

  my skin thickness has gone down as well, possibly even dandruff.

  if ibwas to attempt to make the same kind of medicine, it would be something like honey, citric (vinegar), sulfur & nitrogen from streamed plant biomass.

  added all together, slowly steamed until caramelized.

  Thiamine B1 is documented to cycle repair metabolism enzymes for 3 weeks to a month.

  its a vitamin & medicine, but does require other things to make it continue going.

  Quinine Hydroxychloroquine is said to last a month as well.

  the trick is Heterocyclic Compounds compose of over 50 million known examples.

  but requires very specific factors to get them flipping enzyme reactions

  its not important to get the exact Heterocyclic Compound arrangement, just to get them moving along the correct enzymatic pathways, apposed to building up plaques.

  i suspect if the enzymes move along correctly for long enough, it will not only dissolve biofilm, amyloid plaque, hydrogels, but eventually break down the parasitic or pathogenic host via pathways; prion, viruses ect..

  or knock the parasite to learning how to behave nicely, and protect the immune system.

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